Expert Consultations: Real-World Answers

Psychiatric Pharmacogenomics – Interview

Published on March 1, 2020 Expired on April 1, 2023

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Dana Wang

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Interview Highlights

For poor metabolizers of 2C19, citalopram dosage should not exceed 20 mg, as recommended by the FDA, and that applies to about 20% of the Caucasian population.
Poor metabolizers of 2C19 may actually benefit more from citalopram or escitalopram, even though they may experience more initial side effects.
Without doing genetic testing, we cannot reliably predict who will be a poor metabolizer based only on whether or not patients experience more side effects than usual.

Text Version

This edition of Psychopharmacology Institute’s Expert Interviews features Simon Kung, M.D. Dr. Kung is an associate professor of psychiatry at Mayo Clinic. In this interview, he will be discussing pharmacogenetic testing in psychiatry, with a focus on how to make genetic testing more useful when carrying out clinical decisions.

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Learning Objectives:

After completing this activity, the learner will be able to:

Identify patients who can benefit from pharmacogenetic testing.
Use results from pharmacogenetic testing to guide clinical decisions.

Original Release Date: March 1, 2020

Review and Re-release Date: March 1, 2023

Expiration Date: April 1, 2023

Relevant Financial Disclosures:

Simon Kung declares the following interests:

- Psychopharmacology Institute: role in producing CME presentation

All of the relevant financial relationships listed above have been mitigated by Medical Academy and the Psychopharmacology Institute.

Contact Information: For questions regarding the content or access to this activity, contact us at support@psychopharmacologyinstitute.com

Instructions for Participation and Credit:

Participants must complete the activity online during the valid credit period that is noted above.

Follow these steps to earn CME credit:

View the required educational content provided on this course page.
Answer the quiz for promoting retention of knowledge.
Complete the Post Activity Evaluation for providing the necessary feedback for continuing accreditation purposes and for the development of future activities. NOTE: Completing the Post Activity Evaluation after the quiz is required to receive the earned credit.
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Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of Medical Academy LLC and the Psychopharmacology Institute. Medical Academy is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statement

Medical Academy designates this enduring activity for a maximum of 0.5 AMA PRA Category 1 credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Simon Kung, M.D.