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Open Access Article

Neurological side effects of antipsychotics: akathisia, dystonia and parkinsonism

Published on September 21, 2015 Expired on November 30, 2020

Flavio Guzmán, M.D.

Editor - Psychopharmacology Institute

This video summarizes acute neurological side effects of antipsychotics: akathisia, dystonia and parkinsonism.

Akathisia and Dystonia

  • A classification of neurological side effects
  • Akathisia ( Clinical features, a clinical video, medications that can cause akathisia and management)
  • Acute dystonia (Clinical features, pathophysiology, management)

Parkinsonism

  • Clinical features
  • Mechanism of EPS
  • Differences between antipsychotic-induced parkinsonism and Parkinson’s disease
  • Management of antipsychotic-induced parkinsonism
  • Risk of EPS and D2 occupancy

References and further reading

  • Brunton LB, Lazo JS, Parker KL, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 12th ed. New York: McGraw-Hill; 2010.
  • Janicak, P G., S R. Marder, and M N. Pavuluri. Principles and Practice of Psychopharmacotherapy. 5th ed. Philadelphia: Lippincott Williams & Wilkins, 2010.
  • Stahl, S M. Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications. 3rd ed. New York: Cambrigde University Press; 2008
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