Smita Das, M.D., Ph.D., M.P.H.

A discussion on medications for opioid use disorder, highlighting initiation timing differences between methadone, buprenorphine, and naltrexone. Key topics include preventing precipitated withdrawal, addressing early medication depletion, and maintaining treatment despite positive tests for other substances.

In this video lecture, Dr. Das provides an in-depth exploration of opioid use disorder (OUD) and its management. The lecture begins with an overview of substance use and opioid misuse, followed by a detailed examination of opioid intoxication and withdrawal. It then offers a comprehensive guide to OUD treatment, emphasizing the importance of tailored patient assessment for effective treatment outcomes. Dr. Das also discusses the use of methadone and buprenorphine for managing OUD, as well as the efficacy of extended-release naltrexone. The role of naloxone in managing OUD is highlighted, along with a clinical case illustrating the initiation of buprenorphine treatment.