Our Faculty

Oliver Freudenreich, M.D.

Oliver Freudenreich, M.D.

Co-director of the MGH Psychosis Clinical and Research Program
Associate Professor of Psychiatry
Harvard Medical School

Biography

Dr. Oliver Freudenreich, M.D., FACLP, is an associate professor of psychiatry at Harvard Medical School and a psychiatrist at Massachusetts General Hospital (MGH), serves as co-director of the MGH Psychosis Clinical and Research Program, and directs the MGH Fellowship in Public and Community Psychiatry. His academic interest lies in the area of optimal psychopharmacological treatment for schizophrenia, including the development of innovative treatments and management of treatment-resistant psychosis.

Dr. Freudenreich provides psychiatric consultations for medically complex patients with serious mental illness and for diagnostically difficult cases with psychosis. He also serves on local and national committees related to disaster preparedness. He has published extensively in his areas of interest and has written a handbook on psychotic disorders; its second edition was published in 2020. He teaches and speaks on a regular basis at international and national meetings.

His recent awards include the MGH Department of Psychiatry Clinical Excellence Award and the 2022 Outstanding Psychiatrist Award for the Public Sector from the Massachusetts Psychiatric Society.

Publications of Oliver Freudenreich, M.D.

Quick Take Vol. 82

0.50 CMEs
What are the six key tips for switching oral antipsychotics? Does deprescribing antipsychotics after delirium improve outcomes in older adults? Why is xylazine overdose difficult to treat? What does the PAX-D study reveal about pramipexole for depression? Do bioequivalent medications always produce equivalent clinical results?
Faculty: Oliver Freudenreich, M.D., Scott R. Beach, M.D., David A. Gorelick, M.D., Ph.D., D.L.F.A.P.A., F.A.S.A.M., Paul Zarkowski, M.D., Derick E. Vergne, M.D.
36.44 minutes in 5 audio sections

Quick Take Vol. 81

0.50 CMEs
Can ondansetron improve negative symptoms in schizophrenia? Will lithium orotate prevent or reverse Alzheimer's disease? What predicts treatment response in bipolar disorder? Should we increase SSRI doses or try alternative strategies for inadequate response? Is trazodone safe for treating insomnia in alcohol use disorder?
Faculty: Oliver Freudenreich, M.D., Scott R. Beach, M.D., Kristin Raj, M.D., Paul Zarkowski, M.D., David A. Gorelick, M.D., Ph.D., D.L.F.A.P.A., F.A.S.A.M.
36.33 minutes in 5 audio sections

Managing Side Effects of Antipsychotics: What Every Psychiatrist Should Know – Interview

0.50 CMEs
A discussion on managing antipsychotic side effects, covering strategies for sedation, weight gain, hyperprolactinemia, cardiac risks, and constipation. Key topics include metformin use, clozapine-related complications, and the importance of prophylactic interventions rather than waiting for side effects to develop.
Oliver Freudenreich, M.D.
Massachusetts General Hospital
37.27 minutes of audio interview

Quick Take Vol. 80

0.75 CMEs
How effective is the new antipsychotic KarXT using the number needed to treat metric? Can bright light therapy effectively treat bipolar depression without causing mania? Does IV haloperidol really increase cardiac risks as commonly believed? Can varenicline help reduce alcohol intake in people with alcohol use disorder? Does ashwagandha extract improve cognitive function in mild cognitive impairment?
Faculty: Oliver Freudenreich, M.D., Kristin Raj, M.D., Scott R. Beach, M.D., David A. Gorelick, M.D., Ph.D., D.L.F.A.P.A., F.A.S.A.M., Derick E. Vergne, M.D.
39.35 minutes in 5 audio sections

Quick Take Vol. 79

0.75 CMEs
How should clozapine monitoring change after FDA's REMS removal? Does cariprazine work equally well in older adults with bipolar disorder? Can semaglutide help treat alcohol use disorder? Why do older adults receive subtherapeutic antidepressant doses? Is saffron as effective as SSRIs for depression?
Faculty: Scott R. Beach, M.D., Oliver Freudenreich, M.D., David A. Gorelick, M.D., Ph.D., D.L.F.A.P.A., F.A.S.A.M., Kristin Raj, M.D., Derick E. Vergne, M.D.
44.22 minutes in 5 audio sections

Quick Take Vol. 78

0.50 CMEs
Can pramipexole help treatment-resistant bipolar depression? Does semaglutide work for clozapine-induced obesity? Which antipsychotics best prevent hospitalization after cannabis-induced psychosis? What treatments rank highest for treatment-resistant depression? How do gut microbiota differ in depression versus anxiety disorders?
Faculty: Kristin Raj, M.D., Oliver Freudenreich, M.D., Paul Zarkowski, M.D., Derick E. Vergne, M.D., David A. Gorelick, M.D., Ph.D., D.L.F.A.P.A., F.A.S.A.M.
34.08 minutes in 5 audio sections

Quick Take Vol. 77

0.75 CMEs
What is the best antipsychotic for first-episode psychosis? Can lurasidone treat bipolar depression with severe anxiety? How much do SSRIs increase bleeding when combined with anticoagulants? Is adding salt to meals associated with depression and anxiety?
Faculty: Scott R. Beach, M.D., Paul Zarkowski, M.D., Oliver Freudenreich, M.D., Kristin Raj, M.D., Derick E. Vergne, M.D.
39.21 minutes in 5 audio sections

Quick Take Vol. 76

0.75 CMEs
Can lumateperone effectively treat depression with mixed features? Can GLP-1 agonists manage antipsychotic-induced weight gain? Is quetiapine superior to lithium for treatment-resistant depression? Do antidepressants accelerate cognitive decline in dementia patients? How do probiotics and prebiotics affect depression, anxiety, and cognition?
Faculty: Scott R. Beach, M.D., Paul Zarkowski, M.D., Oliver Freudenreich, M.D., Kristin Raj, M.D., Derick E. Vergne, M.D.
44.56 minutes in 5 audio sections

Quick Take Vol. 75

0.75 CMEs
What are the main considerations when choosing an antipsychotic for first-episode psychosis? How do side effects of antidepressants change over time? Do combinations of psychiatric medications increase Torsades risk? Is there sufficient evidence for psychedelics in treating substance use disorders? Can tea compounds benefit mood and sleep disorders through neurotransmitter modulation?
Faculty: David A. Gorelick, M.D., Ph.D., D.L.F.A.P.A., F.A.S.A.M., Scott R. Beach, M.D., Paul Zarkowski, M.D., Oliver Freudenreich, M.D., Derick E. Vergne, M.D.
40.11 minutes in 5 audio sections

Quick Take Vol. 74

0.75 CMEs
What are the main reasons disulfiram is underutilized for alcohol use disorder? How do different antipsychotics compare regarding QT prolongation risks? What is the optimal dosage of lurasidone for bipolar depression ? How does clozapine's effectiveness compare to other antipsychotics? Which non-benzodiazepine medication options show the best balance of efficacy and side effects for insomnia in psychiatric patients?
Faculty: David A. Gorelick, M.D., Ph.D., D.L.F.A.P.A., F.A.S.A.M., Scott R. Beach, M.D., Paul Zarkowski, M.D., Oliver Freudenreich, M.D., Kristin Raj, M.D.
41.07 minutes in 5 audio sections

Quick Take Vol. 73

0.75 CMEs
How do LAI antipsychotics impact mortality rates compared to oral medications in schizophrenia ? What dosages of medications are most effective for preventing bipolar disorder relapse and maintaining safety? Is olanzapine more effective than risperidone for managing BPS? Can lisdexamfetamine effectively treat methamphetamine use disorder? Does chronopharmacology impact psychiatric treatment efficacy and side effects?
Faculty: David A. Gorelick, M.D., Ph.D., D.L.F.A.P.A., F.A.S.A.M., Scott R. Beach, M.D., Oliver Freudenreich, M.D., Kristin Raj, M.D., Derick E. Vergne, M.D.
43.14 minutes in 5 audio sections

Managing Side Effects of Antipsychotics: What Every Psychiatrist Should Know

1.25 CMEs
A review on antipsychotic side effect management. It offers practical strategies for addressing metabolic concerns, movement disorders, and cardiac complications.
Oliver Freudenreich, M.D.
Massachusetts General Hospital
69.28 minutes in 12 sections
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