Our Faculty

Lauren Osborne, M.D.

Lauren Osborne, M.D.

Vice Chair of Clinical Research in the Department of Obstetrics and Gynecology

Weill Cornell Medicine

Biography

Lauren M. Osborne, M.D., graduated from Weill Cornell Medical College and received her training at Columbia University / New York State Psychiatric Institute. She completed both clinical and research fellowships in women's mental health, and is an expert on the diagnosis and treatment of mood and anxiety disorders during pregnancy, the postpartum, the premenstrual period, and perimenopause.

Dr. Osborne serves as Vice Chair of Clinical Research in the Department of Obstetrics and Gynecology at Weill Cornell Medicine. Her research focuses on the biological mechanisms of perinatal mental illness, with a focus on neurosteroids and the immune system. She also runs the Psychoneuroimmunology in Pregnancy and Postpartum (PIPPI) Lab at Weill Cornell.

Her clinical work consists of collaborative care for perinatal mental health within OB/GYN. She is also chair of the Education Committee for Marcé of North America; founder and chair of the National Curriculum in Reproductive Psychiatry, a free web-based standardized curriculum; and an editor of The APA Textbook of Women’s Reproductive Mental Health. Her work has been supported by the Brain and Behavior Foundation, the Doris Duke Foundation, the American Board of Psychiatry and Neurology, and the National Institute of Mental Health.

Publications of Lauren Osborne, M.D.

Understanding Postpartum Mood Disorders: A Comprehensive Guide – Interview

0.50 CMEs
A discussion on postpartum mood disorders highlighting how to differentiate postpartum blues from depression, treatment approaches including SSRIs and zuranolone, medication considerations while breastfeeding, bipolar disorder screening, and distinguishing postpartum OCD's intrusive thoughts from postpartum psychosis's delusional thinking.
Lauren Osborne, M.D.
Weill Cornell Medicine
26.54 minutes of audio interview

Understanding Postpartum Mood Disorders: A Comprehensive Guide

1.25 CMEs
A review of postpartum mood disorders, focusing on diagnosis, treatment options, and the importance of early intervention. It covers the prevalence, risk factors, and clinical presentations of postpartum depression, psychosis, and OCD, as well as discussing pharmacological and non-pharmacological treatment approaches, including newly approved medications.
Lauren Osborne, M.D.
Weill Cornell Medicine
73.5 minutes in 12 sections

Quick Take Vol. 56

0.75 CMEs
In this Quick Take volume, our expert faculty examine research on the possible effects of prenatal exposure to antidepressants across various trimesters of gestation as well as the safety and efficacy of lithium augmentation for the management of treatment-resistant depression. Our faculty also discuss studies regarding antipsychotics and liver safety as well as inappropriate medication use among older adults.
Faculty: Vivien K. Burt, M.D., Ph.D., Scott R. Beach, M.D., Paul Zarkowski, M.D., Lauren Osborne, M.D., Sydney M. LeFay, D.O.
38.05 minutes in 5 audio sections

Understanding the Use of Psychotropic Drugs in Lactation – Interview

0.75 CMEs
In this interview, Dr. Lauren Osborne highlights practical considerations regarding the use of psychotropic medications, such as antidepressants, mood stabilizers, and antipsychotics, during lactation. She guides clinicians through the process of medication selection using evidence-based research for patients with psychiatric conditions who wish to breastfeed.
Lauren Osborne, M.D.
Weill Cornell Medicine
39.44 minutes of audio interview - Expired on August 1, 2025

Premenstrual Mood Syndromes – Interview

0.50 CMEs
In this interview, Dr. Lauren Osborne discusses premenstrual mood syndromes, specifically risk factors and biological mechanisms underlying these. She also offers valuable insights regarding its management and discusses the use of novel medications, such as brexanolone and drospirenone, for the treatment of these syndromes.
Lauren Osborne, M.D.
Weill Cornell Medicine
36.03 minutes of audio interview - Expired on April 1, 2025

Understanding the Use of Psychotropic Drugs in Lactation

1.00 CMEs
In this presentation, Dr. Lauren Osborne addresses the use of psychotropic drugs in lactation. The presentation includes tools to determine the infant’s exposure to drugs, considerations during breastfeeding, and the possible adverse effects for the baby. Finally, she discusses the risks of using different classes of medications while breastfeeding, such as antidepressants, antipsychotics, and mood stabilizers, and presents various clinical vignettes explaining how to approach each case.
Lauren Osborne, M.D.
Weill Cornell Medicine
66.56 minutes in 10 sections - Expired on April 1, 2025

Premenstrual Mood Syndromes

1.00 CMEs
In this presentation, Dr. Lauren Osborne discusses premenstrual mood syndromes, including definition, assessment, and the differences between PMS, PMDD, and PME. She also reviews treatment options, like lifestyle changes, calcium supplementation, CBT, and pharmacologic treatments. The latter includes SSRIs, symptomatic treatments, and oral contraceptive pills.
Lauren Osborne, M.D.
Weill Cornell Medicine
50.48 minutes in 10 sections - Expired on April 1, 2024

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