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Two horses are flying down the racetrack and down the backstretch. It’s Seabiscuit and War Admiral. They’re neck and neck. Rounding the final turn, Seabiscuit is pulling ahead. It’s Seabiscuit by 3 lengths, now 4 lengths, and it’s Seabiscuit across the line far ahead. Whew!
Hi! Jim Phelps here for the Psychopharmacology Institute. Psychiatry doesn’t see very many horserace studies. That’s the jargon term for trials in which 2 of the top treatment options for an illness are pitted against one another. In most randomized trials, there’s an active treatment group, and the comparison group gets a placebo or an active comparator, like midazolam in a ketamine trial. But we don’t get a direct head-to-head comparison of 2 top treatments very often, which is sad because when you’re trying to make a decision on which treatments to offer your patient, you often have 2 good choices. Which one is better?
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