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Section Free  - Video Lectures

07. Lamotrigine Is Not Slow: Comments About Its Efficacy in Bipolar Depression

Published on February 1, 2018 Expired on April 1, 2021

James Phelps, M.D.

Research Editor - Psychopharmacology Institute

Key Points

  • Overall, lamotrigine is not much slower than antidepressants to produce benefit
  • If the patient has dangerously severe symptoms, other treatments like ECT and olanzapine are much faster
  • Patients tend to choose medications based on tolerability, not speed

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Transcript

 

References

  1. Brown, E. B., McElroy, S. L., Keck Jr, P. E., Deldar, A., Adams, D. H., Tohen, M., & Williamson, D. J. (2006). A 7-week, randomized, double-blind trial of olanzapine/fluoxetine combination versus lamotrigine in the treatment of bipolar I depression . The Journal of clinical psychiatry, 67(7), 1025-1033.
  2. Phelps, J. R. (2016). A spectrum approach to mood disorders: not fully bipolar but not unipolar: practical management . New York: W. W. Norton & Company.

Learning Objectives:

After completing this activity, the learner will be able to:

  1. Describe the concept of the bipolar spectrum as a dimensional approach to mood disorders
  2. Review the efficacy, safety and practical uses of lamotrigine

Original Release Date: 02/01/2018

Expiration Date: 04/01/2022

Relevant Financial Disclosures: 

The following planners, faculty, and reviewers have the following relevant financial relationships with commercial interests to disclose:

Dr. Phelps has disclosed the following relationships:

  • McGraw-Hill, W.W. Norton & Company: Books on bipolar disorders
  • McGraw-Hill: Book on Bipolar II / Bipolar NOS
  • W.W.Norton & Co.: Books on a spectrum approach to mood disorders

All of the relevant financial relationships listed for these individuals have been mitigated.

Contact Information: For questions regarding the content or access to this activity, contact us at support@psychopharmacologyinstitute.com

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