12. Try a Second SSRI or an Alternative (Node 4)
Key Points
- After failure on an initial SSRI, a second SSRI is the standard recommendation
- SSRIs are not identical in spectra of receptor activity
- A different SSRI might have a better constellation of effects
- Other alternatives at this point include: buspirone, hydroxyzine, pregabalin, bupropion, benzodiazepines, venlafaxine and herbs (Kava, Rhodiola rosea, and lavender oil)
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