03. QTc Prolongation with Citalopram: Evidence and Controversy
Key Points
- There is evidence that citalopram causes more QT prolongation than other SSRIs. It is associated with QT prolongation on the order of 10 ms to 20 ms.
- Citalopram does not appear to be associated with higher rates of torsade or other ventricular arrhythmias.
- Reflexively lowering the dose of citalopram due to concerns about QT prolongation may lead to adverse psychiatric outcomes.
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