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In part 1 of this 2-part Quick Take, we began with the question, 30% to 50% of adolescents with depression don’t respond to their first treatment, and about 10% don’t improve despite multiple trials of standard treatments, so what else can we do?
Hi! Jim Phelps here for the Psychopharmacology Institute. We’re looking at a review of treatment options for just this circumstance by Kathryn Cullen and colleagues. Part 1 focused on the TADS Study, especially adolescent CBT. Here, in part 2, we’ll look at other modalities, such as sensorimotor interventions like yoga, physical activity, and light therapy; nutraceuticals; and neuromodulations, like ECT and TMS.
Is there enough clout in these treatments to consider them before a next antidepressant? Consider yoga as a treatment for depression. In a randomized trial in adults, the effect size was very large at 0.96, but the controls in that group got yoga history modules
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