Slides and Transcript
Slide 2 of 11
You see on the left side a body map.
There are 19 sites on this body map and people are asked to check all the sites they have pain.
References:
- Clauw, D. J. (2014). Fibromyalgia. JAMA, 311(15), 1547.
- Wolfe, F., Clauw, D. J., Fitzcharles, M. A., Goldenberg, D. L., Häuser, W., Katz, R. S., Mease, P., Russell, A. S., Russell, I. J., & Winfield, J. B. (2011). Fibromyalgia criteria and severity scales for clinical and epidemiological studies: A modification of the ACR preliminary diagnostic criteria for fibromyalgia. The Journal of Rheumatology, 38(6), 1113–1122.
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Slide 3 of 11
And you add up from 0 to 19 how many sites people have pain in.
And this measure is called the Widespread Pain Index and it just gives you an extent of how widespread the pain is. And just the body map alone will help predict for example, which individuals with low back pain or osteoarthritis respond to a drug like duloxetine that is working in the amplifier, in the central nervous system.
References:
- Clauw, D. J. (2014). Fibromyalgia. JAMA, 311(15), 1547.
- Wolfe, F., Clauw, D. J., Fitzcharles, M. A., Goldenberg, D. L., Häuser, W., Katz, R. S., Mease, P., Russell, A. S., Russell, I. J., & Winfield, J. B. (2011). Fibromyalgia criteria and severity scales for clinical and epidemiological studies: A modification of the ACR preliminary diagnostic criteria for fibromyalgia. The Journal of Rheumatology, 38(6), 1113–1122.
Slide 4 of 11
People are asked about central nervous system symptoms that are phenotypic markers of nociplastic pain or fibromyalgia. They’re asked about fatigue, memory problems, and sleep disturbances. Those are scored from 0, 1, 2, or 3 based on whether they’re not there, slight, moderate, or severe.
References:
- Clauw, D. J. (2014). Fibromyalgia. JAMA, 311(15), 1547.
- Wolfe, F., Clauw, D. J., Fitzcharles, M. A., Goldenberg, D. L., Häuser, W., Katz, R. S., Mease, P., Russell, A. S., Russell, I. J., & Winfield, J. B. (2011). Fibromyalgia criteria and severity scales for clinical and epidemiological studies: A modification of the ACR preliminary diagnostic criteria for fibromyalgia. The Journal of Rheumatology, 38(6), 1113–1122.
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Slide 5 of 11
And then people are asked about irritable bowel, depression, or headache and they get 1 point each for those questions.
References:
- Clauw, D. J. (2014). Fibromyalgia. JAMA, 311(15), 1547.
- Wolfe, F., Clauw, D. J., Fitzcharles, M. A., Goldenberg, D. L., Häuser, W., Katz, R. S., Mease, P., Russell, A. S., Russell, I. J., & Winfield, J. B. (2011). Fibromyalgia criteria and severity scales for clinical and epidemiological studies: A modification of the ACR preliminary diagnostic criteria for fibromyalgia. The Journal of Rheumatology, 38(6), 1113–1122.
Slide 6 of 11
So a total of 0 to 19 points based on how widespread the pain is on the body map.
A score from 0 to 9 points based on whether people have and how severe their fatigue, memory problems, and sleep disturbance are, and then a total of 3 points for just the presence or absence of irritable bowel, depression, or headache.
References:
- Clauw, D. J. (2014). Fibromyalgia. JAMA, 311(15), 1547.
- Wolfe, F., Clauw, D. J., Fitzcharles, M. A., Goldenberg, D. L., Häuser, W., Katz, R. S., Mease, P., Russell, A. S., Russell, I. J., & Winfield, J. B. (2011). Fibromyalgia criteria and severity scales for clinical and epidemiological studies: A modification of the ACR preliminary diagnostic criteria for fibromyalgia. The Journal of Rheumatology, 38(6), 1113–1122.
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Slide 7 of 11
This score from 0 to 31, if someone has a score of 13 or higher, they are said to be diagnosed with fibromyalgia.
References:
- Clauw, D. J. (2014). Fibromyalgia. JAMA, 311(15), 1547.
- Wolfe, F., Clauw, D. J., Fitzcharles, M. A., Goldenberg, D. L., Häuser, W., Katz, R. S., Mease, P., Russell, A. S., Russell, I. J., & Winfield, J. B. (2011). Fibromyalgia criteria and severity scales for clinical and epidemiological studies: A modification of the ACR preliminary diagnostic criteria for fibromyalgia. The Journal of Rheumatology, 38(6), 1113–1122.
Slide 8 of 11
But one of the things that I think is really important to realize or understand is that all the data about nociplastic pain or fibromyalgia suggest that this is never just present or absence. Different people have different degrees of this.
References:
- Clauw, D. J. (2014). Fibromyalgia. JAMA, 311(15), 1547.
- Wolfe, F. (2009). Fibromyalgianess. Arthritis & Rheumatism, 61(6), 715-716.
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Slide 9 of 11
And the term fibromyalgianess was coined by Fred Wolfe many years ago to connote this.
And he said that if you basically look at the degree of fibromyalgia that someone with osteoarthritis or rheumatoid arthritis or lupus has, that’s often a stronger predictor of how much pain or disability they have than our more objective measures of that disease like an x-ray or a sedimentation rate or a C-reactive protein.
And so what we see is that the higher degree of fibromyalgianess is really just saying the same is that they have more central sensitization, more nociplastic pain.
References:
- Clauw, D. J. (2014). Fibromyalgia. JAMA, 311(15), 1547.
- Wolfe, F. (2009). Fibromyalgianess. Arthritis & Rheumatism, 61(6), 715-716.
Slide 10 of 11
And so the new criteria for fibromyalgia nociplastic pain, look for a combination of more widespread pain, comorbid sleep, memory, and fatigue issues as well as irritable bowel, depression or headache.
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