01. Defining the Bipolar Spectrum
Key Points
- Low-dose lithium has demonstrated efficacy for depression at both ends of the spectrum
- CBT-IB (Cognitive Behavioral Therapy for Insomnia, Bipolar version) has evidence of efficacy for treatment of mid-spectrum depression and mixed states
- Lamotrigine should be one of the first options considered for a patient whose depression is clearly more than unipolar
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