05. Adverse Effects of Antipsychotics in Elderly Patients
Key Points
- Orthostatic hypotension
- Aripiprazole, lurasidone and ziprasidone have low affinity for alpha-1 receptors
- It can be minimized using small, divided oral doses and titrating slowly
- Metabolic effects
- Aripiprazole, asenapine, lurasidone, paliperidone and ziprasidone confer the least risk
- Extrapyramidal effects
- Quetiapine and iloperidone confer a low risk
- Clozapine is devoid of EPS
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