Section - CAP Smart Takes

05. A Web-Based Pediatric Drug Information System to Prevent Serious Adverse Drug Reactions

Published on February 1, 2023 Certification expiration date: February 1, 2026

David R. Rosenberg, M.D.

Chair of the Department of Psychiatry & Behavioral Neuroscience - Wayne State University School of Medicine

Key Points

Psychotropic medications are often prescribed off-label in youth. Thus, they are at increased risk or even unknown risk for serious adverse drug reactions.
Many serious adverse drug reactions can be potentially reversible using a web-based pediatric drug information system.
Using a web-based pediatric drug information system could also prevent prolonged hospital stays.

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Text version

Hi! David Rosenberg here for the Psychopharmacology Institute. In this CAP—or Child and Adolescent Psychiatry—Smart Take, we will look at how a web-based drug information system developed in Germany could prevent prescribing errors and serious adverse drug reactions in children and adolescents with psychiatric disorders. It includes dosing recommendations and pharmaceutical and pharmacologic information for various drugs used in children and adolescents in Germany. So, psychotropic medications are more frequently prescribed off-label in children and adolescents than adults. So, children and adolescents with mental disorders are at increased risk or even unknown risk for serious adverse drug reactions.

Moreover, the authors looked at child and adolescent inpatients and examined the preventability or lack thereof of serious adverse drug reactions by following the recommendations of a web-based pediatric drug information system. They screened over 1,000 patients, about 64% receiving psychotropic medication treatment. In over 8% of these patients, 54 serious adverse

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Learning Objectives:

Recognize that pharmacologic and nonpharmacologic interventions have large beneficial effects when combined.
Identify that viloxazine ER can significantly reduce learning and school problems and clinical ADHD symptoms.
Acknowledge that antipsychotic and antidepressant prescriptions remained high in September 2020 and had not decreased or returned to prepandemic levels.
Understand that lisdexamfetamine was well tolerated in preschool children with ADHD, with no new safety signals observed.
Recognize that a web-based pediatric drug information system can help prevent prescribing errors.

Original Release Date: February 1, 2023

Review and Re-release Date: March 1, 2024

Expiration Date: February 1, 2026

Expert: David Rosenberg, M.D.

Relevant Financial Disclosures:

None of the faculty, planners, and reviewers for this educational activity have relevant financial relationships to disclose during the last 24 months with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

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This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of Medical Academy LLC and the Psychopharmacology Institute. Medical Academy is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation Statement

Medical Academy designates this enduring activity for a maximum of 0.5 AMA PRA Category 1 credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.