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For our next Quick Take, here’s a review of an article with a pretty good come-hither title, “How to Choose an Antidepressant?” This article is by one of our most experienced colleagues, Gordon Parker, who is the main man behind Australia’s prestigious Black Dog Institute, with his colleague there, Adam Bayes. I’m going to synthesize their article and arrive at a very simple conclusion based on it and on some of its key references.
So, how do you decide which antidepressant to offer a patient if they’ve never had one? I’m going to suggest that since no antidepressant clearly stands out above the rest, the decision is actually best made by asking the patient what they know about antidepressants. For example, you might say, “There are a lot of antidepressants out there. You may know about some of them. Has anyone in your family ever taken one?” And if that
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