Methylphenidate is a CNS stimulant approved for the treatment of narcolepsy and attention deficit hyperactivity disorder (ADHD). It inhibits the reuptake of dopamine and norepinephrine, increased dopaminergic and noradrenergic activity in the prefrontal cortex may explain its efficacy in ADHD.
This tutorial reviews mechanism of action and relevant features of methylphenidate formulations.
This presentation reviews the essential aspects of this medication including: mechanism of action, indications, pharmacokinetics, adverse effects profile and dosing guidelines.
This video discusses the role of 5-HT1A receptor downregulation in the mechanism of action of SSRIs. The monoamine theory of depression is also reviewed and contrasted with its limitations.
This brief video is an overview on the most common side effect of selective serotonin reuptake inhibitors.
Possible mechanisms for each side effect are also discussed.
PDF: LAI Antipsychotics
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- New formulations (Aristada, Invega Trinza)
- Practical dosing tables