Unbiased and Practical Psychopharmacology Updates

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TRENDING IN PSYCHOPHARMACOLOGY INSTITUTE

Quick Takes

The latest research that matters to your practice. CME available.

Switching Oral Antipsychotics: Six Strategies and Tips

Benzodiazepine Tapering: Key Takeaways From New Guidelines

Deprescribing Antipsychotics Post-Delirium: Why It Matters

Is Ondansetron Effective for Negative Symptoms in Schizophrenia?

Lithium Orotate: Breakthrough Treatment for Alzheimer’s Disease?

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Brain Guides

Guides distilling the literature for confident prescribing. CME available.

Tricyclic Antidepressants in Psychiatry: Selection and Prescribing

Serotonin Syndrome: Mechanisms, Diagnosis, High-Risk Interactions, and Management

Antidepressants and Metabolic Disturbances

Gastrointestinal Side Effects of Antidepressants: Mechanisms, Comparison and Management Strategies

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Video Lectures

A selection of practical sections from our video lectures. CME available for Bronze, Silver, and Gold members.

Initiating and Optimizing Clozapine

Treating Anxiety Disorders in Patients With Cancer

Prevalence, Assessment, and Management of RBD

Considerations for Using Benzodiazepines and Benzodiazepine Receptor Agonists in the Geriatric Population

Use of Omega-3 Fatty Acids in Children and Adolescents

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RECENT PUBLICATIONS

PTSD Psychopharmacology Algorithm

1.50 CMEs
An updated algorithm for PTSD that prioritizes prazosin for sleep disturbances and nightmares before SSRIs. The presentation reviews evidence-based dosing for men and women, sleep initiation alternatives, second-line antidepressants, antipsychotics for PTSD-related psychosis, augmentation options, and considerations for comorbid substance use and bipolar disorder.
David Osser, M.D.
Harvard Medical School
83.49 minutes in 12 sections

Prescribing Tricyclic Antidepressants Safely: Drug Interactions, Side Effects, and Overdose

0.50 CMEs
This guide addresses tricyclic antidepressant safety across the prescribing lifecycle: CYP2D6 inhibitor interactions (fluoxetine, paroxetine, bupropion), CPIC-guided dosing in poor and ultrarapid metabolizers, a structured monitoring framework, agent selection across pregnancy, breastfeeding, and older adults, and overdose recognition.
Sebastián Malleza, M.D.
Psychopharmacology Institute
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Ketamine and Esketamine: State of The Art – Interview

0.50 CMEs
A discussion with on ketamine and esketamine for treatment-resistant depression, covering regulatory differences, patient selection, placement in the treatment algorithm, maintenance and tapering, managing dissociative and dysphoric reactions, nausea, clinic workflow, bipolar and geriatric populations, and choosing between IV ketamine and esketamine.
Samuel Wilkinson, M.D.
Yale University School of Medicine
32.13 minutes of audio interview

Tricyclic Antidepressants in Psychiatry: Selection and Prescribing

0.50 CMEs
This guide examines tricyclic antidepressants as second- or third-line agents, covering the tertiary vs. secondary amine distinction and its implications for tolerability, a clinical decision framework for agent selection, AGNP-guided therapeutic drug monitoring with reference ranges for all six commonly used agents, dosing and titration strategies, and switching protocols.
Sebastián Malleza, M.D.
Psychopharmacology Institute
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Management of Psychotropic-Induced Sexual Dysfunction

1.0 CMEs
A review of sexual dysfunction related to psychotropic medications, covering neurobiological mechanisms, prevalence across antidepressant and antipsychotic classes, and genetic risk factors. Practical guidance includes validated assessment tools, medication substitution strategies, off-label antidotes, and approaches to address modifiable contributors.
Anita H. Clayton, M.D., D.L.F.A.P.A., I.F.
University of Virginia School of Medicine, Charlottesville, VA
62.33 minutes in 10 sections

Quick Take Vol. 85

0.50 CMEs
Does Cobenfy maintain its efficacy and safety after one year of use? Should we reconsider trazodone for depression-associated insomnia despite AASM guidelines? Is antidepressant monotherapy in bipolar I as risky as previously thought? Does inflammation explain treatment resistance in older depressed adults? What risk factors predict stimulant misuse and diversion in ADHD patients?
Faculty: Scott R. Beach, M.D., Oliver Freudenreich, M.D., David A. Gorelick, M.D., Ph.D., D.L.F.A.P.A., F.A.S.A.M., James Phelps, M.D., Paul Zarkowski, M.D.
33.5 minutes in 5 audio sections

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CME Information

Physicians – CME Accreditation Statement

The activities below have been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Medical Academy LLC and the Psychopharmacology Institute. Medical Academy LLC is accredited by the ACCME to provide AMA PRA Category 1 Credits™ for physicians.

This CME program issues AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

Download Accreditation Information (PDF)

Nursing professionals – CME Accreditation Statement

The activities below have been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Medical Academy LLC and the Psychopharmacology Institute. Medical Academy LLC is accredited by the ACCME to provide AMA PRA Category 1 Credits™ for physicians.

This CME program issues AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

The ANCC accepts AMA PRA Category 1 Credit(s)™ as Contact Hours, under this calculation: 1 CME = 1 Contact Hour. 

Download Accreditation Information (PDF)

Physician assistants – CME Accreditation Statement

The activities below have been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Medical Academy LLC and the Psychopharmacology Institute. Medical Academy LLC is accredited by the ACCME to provide AMA PRA Category 1 Credits™ for physicians.

This CME program issues AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

Download Accreditation Information (PDF)

Self Assessment for MOC – Accreditation Statement
  • Psychopharmacology Institute Self-Assessment Program 2025

Dates: April 1, 2025 – April 1, 2028

The American Board of Psychiatry and Neurology has reviewed the Psychopharmacology Institute Self-Assessment Program 2025 and has approved this activity as part of a comprehensive Self-Assessment activity, which is mandated by the ABMS as a necessary component of Continuing Certification.

  • Psychopharmacology Institute Self-Assessment Program 2024

Dates: April 1, 2024 – April 1, 2027

The American Board of Psychiatry and Neurology has reviewed the Psychopharmacology Institute Self-Assessment Program 2024 and has approved this activity as part of a comprehensive Self-Assessment activity, which is mandated by the ABMS as a necessary component of Continuing Certification.

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